14 results
hematology differential management ai algorithm anemia endocrinology insufficiency leukemia mds myelodysplastic cardiology chronic cll differentiation endocarditis extravascular hemolysis hemolytic infectious
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
Causes of Adrenal ... Polyglandular Autoimmune Syndrome ... • Infectious: ... TB, Disseminated ... Fungal, HIV/AIDS
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Non-lmmune: • HELLP Syndrome ... • TTP/HUS • DIC ... Vasculitis • Infection ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome ... #hematology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... risk-stratification • Risks: infection ... Myelodysplastic #Syndrome ... #hematology #oncology
Infectious Causes of Adrenal Insufficiency Anatomical distribution of vessels to the adrenal makes the gland prone to
Infectious Causes ... infection or disseminated ... Waterhouse-Friderichsen syndrome ... canimorsus • Virus: HIV ... #Causes #Adrenal
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): - Disseminated ... intravascular coagulation (DIC ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... Drugs (Beta lactam antibiotics
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... : Infection (sepsis ... Differentiation #Syndrome ... #APML #diagnosis ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... • Anemia • Aplastic ... isoniazid) • Antibiotics ... #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... develop leukostasis syndrome ... Fibrinolysis & DIC ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Compartment syndrome ... Neuroleptic malignant syndrome ... - Viral (HIV, Influenza ... complication: DIC ... or compartment syndrome
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