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differential management hematology algorithm causes dermatology petechiae sle druginduced erythematosus intravascular purpuric systemic treatment activation anemia bleeding bruising classification coagulation
Algorithm for Diagnosis of the Petechial / Purpuric Rash Febrile/Toxic, Palpable: - Meningococcaemia, Disseminated Gonococcal Infection,
Algorithm for Diagnosis ... / Purpuric Rash ... Meningococcaemia, Disseminated ... Purpura Fulminans, DIC ... #Purpura #Rash
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... Meningococcemia - Disseminated ... fulminans - DIC ... Autoimmune Vasculitis (lupus ... #Petechiae #Rash
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
meningococcemia, disseminated ... purpura fulminans, disseminated ... coagulopathy (DIC ... or purpuric rash ... Purpural #Purpuric #Rash
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Manifestations: Malar rash ... of SLE versus DIL ... Erythematosus #Diagnosis ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... NPSLE rare, Malar rash ... Manifestations: Malar rash ... comparison #table #rheumatology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... : • Petechiae ... #Disseminated # ... #Coagulation #diagnosis ... treatment #management #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Photosensitivity, Butterfly rash ... Endocarditis, Aortic ... signs #symptoms #diagnosis ... #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): - Disseminated ... intravascular coagulation (DIC ... usually IgG) (e.g. lupus ... #hematology #anemia
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor and lupus ... liver failure, disseminated ... disease • Acute DIC ... #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
mucosal bleeding (Petechial ... or purpuric rash ... SJIA], systemic lupus ... Activation #Syndrome #Diagnosis ... #Rheumatology
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