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diagnosis causes differential intravascular abnormal anemia aptt hemolytic prolonged pt algorithm extravascular hemolysis hemorrhage isth laboratory maha management microangiopathic microscopy
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
clot, venous compression ... endocarditis) - Disseminated ... intravascular coagulation ... MAHA: TTP, HUS, DIC ... #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Scoring System for Disseminated ... (DIC) Platelet ... thrombin to form clots ... #Disseminated # ... Scoring #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Coagulation (DIC ... significant fibrin clot ... #Disseminated # ... treatment #management #hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Uterine fatigue (e.g ... Retained blood clots ... HELLP syndrome • Disseminated ... intravascular coagulation ... (DIC) • Anti-coagulation
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... conditions such as disseminated ... intravascular coagulation ... count, D-dimer, egg ... hemolytic #anemia #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): - Disseminated ... intravascular coagulation ... (DIC) - HELLP ... (usually IgG) (e.g ... differential #diagnosis #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Congenital intrinsic coagulation ... Disseminated intravascular ... coagulation (DIC ... #differential #hematology ... #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
inhibitory drugs (e.g ... hemorrhage • Disseminated ... intravascularcoagulation (DIC ... #differential #hematology ... #coagulation
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