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Thrombocytopenia - Differential Diagnosis Algorithm Decreased production: • Bone marrow suppression • Bone marrow failure • Bone
Nutritional Increased destruction ... disorders • Immune destruction ... Consumption • Destruction
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Pathogenesis and Clinical ... pathogen (tag for destruction ... enzyme-mediated destruction
Hypothalamus Anatomy and Hypothalamic Nuclei • Anterior hypothalamic nucleus - Body temperature, thermal regulation (heat dissipation),
parasympathetic ns, destruction ... ADH & oxytocin, destruction ... thermal regulation, destruction ... Satiety center, destruction
Pain Assessment and Management Initiative (PAMI) - Nonpharmacologic Interventions (pediatric and adult) Physical (Sensory) Interventions - Comfort
Assessment and Management ... or coaching - Distraction ... therapeutic language #Management
Causes of Thrombocytopenia. Platelet counts may be depressed because of decreased production or due to increased platelet
increased platelet destruction ... Causes #Production #Destruction
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 Differential Diagnosis of Thrombocytopenia by Categories: - Decreased Production - Increased Destruction - Redistribution #Diagnosis #Thrombocytopenia #Differential #Algorithm #Causes #Ddxof
Production - Increased Destruction
Infective Endocarditis - Diagnosis and Management Summary Pearls: - Consider non-infectious endocarditis in pts with cancer/SLE and
Diagnosis and Management ... phenomenon > valvular destruction ... Endocarditis #Diagnosis #Management
Pancytopenia - Differential Algorithm / Schema - Bone Marrow Failure - Bone Marrow Infiltration - Sequestration / Destruction #Pancytopenia #Differential
Sequestration / Destruction
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
reticulated-plts) • ↑ Destruction ... Production • ↑ Destruction
How to measure your blood pressure at home 1) PREPARE - Avoid caffeine, cigarettes and other stimulants
comfortably without distraction ... quietly with no distractions
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