25 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... • Increased Destruction ... Vascular System ... Coagulation #Bleeding ... Algorithm #Causes #Hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Initial screening test ... • MCTD (SLE/systemic ... Summary #diagnosis #rheumatology ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
IL-1 and IL-6, leading ... purpura to mucosal bleeding ... Liver function tests ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... PT, aPTT(liver disease ... K), H. pylori test ... thyroid function test ... Causes #Workup #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... screening for disease ... with established disease ... Chronic Management ... #treatment #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Cerebrovascular Disease ... inflammation, leading ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Paradoxical spontaneous bleeding ... processes: • Systemic ... rheumatic diseases ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Algorithm for managing FVII deficiency.

*Mild bleeding history includes minor epistaxis, menorrhagia, gastrointestinal bleeding, joint and soft
*Mild bleeding history ... †Severe bleeding ... central nervous system ... Factor7 #Algorithm #management ... #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Von Willebrand’s disease ... cascade is intact - test ... Von Willebrand disease ... liver function tests ... Differential #Diagnosis #Hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... Positive pathergy test ... is a skin prick test ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology