13 results
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The gout drug pegloticase ... a recombinant version ... #Homeostasis #Gout ... Pathophysiology #Pharmacology ... #Medications #Management
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
and Pharmacology ... Hypotension with rapid injection ... diarrhea & abdominal pain ... #Pharmacology # ... hematology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
onset of swelling, pain ... diagnose concomitant infection ... Metabolic syndrome • Medications ... swelling, significant pain ... #Comparison #rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... Metabolic syndrome • Medications ... swelling, significant pain ... Diagnose concomitant infection ... #treatment #rheumatology
Orthopedic Dressing Materials
1. Opsite - semi-permeable-thin, adhesive transparent polyurethrane film 
 • Indications: Superficial wounds as
recommended in anearobic infections ... Contraindications: Dry wound, infection ... with, topical medication ... prone to bleeding, oncology ... Dressings #Materials #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Complications: 1) Infection ... low-risk disease • Indications ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- Antithyroid medications ... Idiopathic • Infections ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
effusions, weight gain ... Differential Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... diagnosis • Rule out ... causes such as infectious ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... hemolytic anemia • Pain ... classification #hematology ... #oncology #management