56 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... elbows/wrists and knees ... interstitial lung disease ... #rheumatology #diagnosis ... #signs #symptoms
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
of IgG4-related disease ... by organ system ... #Organs #Systems ... #Diagnosis #Hematology ... #Signs #Symptoms
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... central nervous system ... important, as early diagnosis ... #differential #diagnosis
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
- Differential Diagnosis ... Infection - Systemic ... disease - Malignancy ... SLE - Behcet Disease ... #differential #diagnosis
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... • Homogeneous: Systemic ... ) • Speckled: Systemic ... • Peripheral: Systemic ... #rheumatology #diagnosis
Sarcoidosis 
Systemic non-caseating granulomatous disease. 
Patients classically have mediastinal hilar lymphadenopathy. 
CXR is abnormal in 90%
Sarcoidosis Systemic ... granulomatous disease ... Sarcoidosis #Signs #Symptoms ... #Diagnosis
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
Dysplastic FDC • Systemic ... symptoms usually ... unicentric • Systemic ... symptoms usually ... #Variants #Diagnosis
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... autoimmune disease ... Lupus - with Systemic ... should have other symptoms ... #Differential #Diagnosis
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) 
An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. 
Affects
Kawasaki Disease ... Syndrome) An rare systemic ... Early diagnosis ... Features #Signs #Symptoms ... #Diagnosis #Peds
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... joints Nervous system ... pain (20%) Renal disease ... erythematosus #signs #symptoms ... #diagnosis #rheumatology