265 results
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Causes include : ... Pre-analytical cause ... effect (FII, FVII, FIX ... Fll, FV, FVII, FIX ... aPTT #Prolonged #Causes
Causes of Diarrhea 
#Diarrhea #DDX
Causes of Diarrhea ... #Diarrhea #DDX
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... HMWK), FXII, FXI, FIX ... Pre-analytical cause ... Fll, FV, FVII, FIX ... aPTT #Prolonged #Causes
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
rigors, diarrhea, nausea ... Ddx? ... Ddx is very broad ... Final dx: Septic ... Rash #clinical #photo
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... Granulomatous DX ... Granulomatous DX ... BrighamChiefs #ILD #Causes
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Negative urine dip ... Positive urine dip ... sediment - WBC/RBC casts ... Diagnosis #Algorithm #Causes
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation (DIC ... helmet cells DDX ... MAHA: TTP/HUS > DIC ... Treat primary cause ... Coagulation #diagnosis #causes
Sebaceous hyperplasia 
 - Yellow papule 
 - Donut-shape 
 - Central umbilication 
 - Telangiectasia
Usually multiple - Causes ... Benign #Clinical #Photo
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
e.g NSAlDs) 3) FIX ... PROBLEM ~80% of AKI cases ... are caused by prerenal ... CONSIDER INTRINSIC CAUSES ... for WBCs, RBCs, casts
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... intravascular coagulation (DIC ... MAHA: TTP, HUS, DIC