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rheumatology differential hepatology primary algorithm antibodies syndrome abnormal ana antinuclear associations autoantibodies cholangitis diseases enzymes erythematosus lfts liver lupus management
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
processes like primary biliary ... cirrhosis (PBC) ... erythematosus (SLE ... ) Signs / Symptoms ... #Signs #Symptoms
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... quadrant discomfort Signs ... #Biliary #Cirrhosis ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... Signs and Symptoms ... #Cirrhosis #PBC ... #workup #hepatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Anti-gp210 - Primary biliary ... cirrhosis (PBC) ... Anti-SSB (La) - Sjogren's ... Associations #diseases #diagnosis ... #table #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... ), Sjogren's Syndrome ... Hepatitis, Primary Biliary ... Cirrhosis, Drug-Induced ... #diagnosis #differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... hepatitis, primary biliary ... cirrhosis: 3%-20% ... Nephrogenic DI Hematologic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Differential Diagnosis ... dermatomyositis, Sjogren ... Kikuchi disease • Type-I ... Induced Lupus: • Symptoms
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... /signs should be ... include extrahepatic biliary ... body mass index; FBC ... disease; T2DM, type
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Presentation - Systemic Symptoms ... purpura: strong sign ... vasculitis, and SLE ... #rheumatology # ... classification
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