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differential management algorithm causes potassium pharmacology syndrome cardiology chf ckd clinical criticalcare defects diuresis diuretics epithelial excretion foamed heartfailure hemodialysis
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Hypocalciuria (spot ... • Seizures • Rhabdomyolysis ... Treatment - ... #Syndrome #diagnosis ... #nephrology #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Differential Diagnosis ... nephrotoxicity to kidney ... per day until stable ... #Differential #Diagnosis ... #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
- Differential Diagnosis ... starts by measuring ... • Renal tubular ... Bartter's syndrome, Gitelman's ... algorithm #causes #nephrology
Gitelman Syndrome - Diagnosis and Workup Blood Work: - Hypokalemia - Hypomagnesemia - Metabolic Alkalosis - Elevated
Gitelman Syndrome ... Blood Work: - Hypokalemia ... autosomal dominant kidney ... of echogenic kidneys ... #Workup #nephrology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... suggests extra-renal ... Bartter syndrome, Gitelman ... #diagnosis #Algorithm ... differential #potassium #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Differential Diagnosis ... oxidative iniury Treatment ... per day until stable ... Dialysis for severe hyperkalemia ... #Differential #Diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
Inherited Defects in Kidney ... Epithelial Cells Renal ... ascending limb Gitelman ... #Nephrology #Diagnosis ... #Differential #Table
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... Villous adenoma Renal ... diuretic use), Gitelman's ... #differential #diagnosis ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... tourniquet / IVF line draw ... 15 suggests ↓ renal ... Elimination (see Table ... #nephrology #K
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Agents Regulating Renal ... disequilibrium syndrome • Diagnosis ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology ... #Medications #Table
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