14 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Leucopenia/lymphopenia, Thrombocytopenia ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... K), H. pylori test ... (GI symptoms/endemic ... thyroid function test ... , ANA (e.g., SLE
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Neurological 12% - Thrombocytopenia ... Lupusreference #SLE ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... Hydroxychloroquine *Short ... #Summary #diagnosis ... #rheumatology # ... management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
approach for post-test ... : Confirmatory test ... ↑Se/Sp but very ... #Diagnosis #Management ... #Treatment #Hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs ... #symptoms #rheumatology
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
Mild anemia • Thrombocytopenia ... • New onset SLE ... Viral hepatitis Diagnosis ... Phase: • The short ... Syndrome #HIV #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... adults in the west ... with no early symptoms ... Physical Exam/Signs ... Neutropenia, anemia, thrombocytopenia
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus [SLE ... leukopenia, anemia, and thrombocytopenia ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... the “Chewing gum test ... them, but urgent rheumatology ... #Symptoms #Diagnosis ... #Management