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diagnosis management rheumatology sclerosis symptoms syndrome aids algorithm als amyotrophic autoimmune behcet bronchiectasis cauda caudaequina causes cmv cord cytomegalovirus disorders
Cytomegalovirus (CMV) in HIV-AIDS Patients Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family. CMV infection: virus isolation or detection
pp65 antigenemia test ... 50 or less: • Neurologic ... Encephalitis, Myelitis ... Pancreatitis • Pulmonary ... association with PJP/TB
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... simplex virus, HIV ... , Hep A/B/CMV, TB ... Treatment: • ... #differential
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
• Symptoms and signs ... - Transverse myelitis ... Treponema, Listeria, TB ... Sarcoidosis, Behcet disease ... disorders #diagnosis #neurology
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
lesion Pott's Disease ... (IRIS): • In HIV ... TB • Many possible ... Tuberculosis #diagnosis #differential ... #TB #neurology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
cord infarct • HIV ... • Transverse myelitis ... • Provocative Tests ... axial T1 and T2 Treatment ... diagnosis #causes #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... disorder (Cardiac, pulmonary ... Lesions of the spinal ... Lack of UMN/LMN signs ... parainfluenza, Coxsackie, HIV
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
• Infection: TB ... Nasal polyps and signs ... , CCP, ANCA • HIV ... mycobacteria Treatment ... #differential #
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... neuritis • Partial myelitis ... Progressive MS (Spinal ... • Acute: - IV ... #treatment #MS
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... white matter, spinal ... ) Differential Diagnosis ... Arthritis, AS Treatment ... diagnosis #management #signs
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Presentation: - Disease ... course of the disease ... conditions listed in differential ... diagnosis column Treatment ... Lateral #Sclerosis #neurology
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