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diagnosis management hematology syndromes behcet bronchiectasis cauda caudaequina causes chronic cll differentiation disease emergencies equina hemeonc immune inflammatory iris leukemia
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Imaging: CXR- pulmonary ... Diagnosis: >3 symptoms ... initiation • Differential ... management #hematology #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... Behcet disease) Differential ... Arthritis, AS Treatment ... management #signs #symptoms
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... • Provocative Tests ... axial T1 and T2 Treatment ... #differential # ... diagnosis #causes #neurology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... • Mounier-Kuhn syndrome ... dyskinesia • Young syndrome ... mycobacteria Treatment ... #differential #
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
coagulopathy) • CBC w differential ... anti-GBM) Other tests ... or serologies + symptoms ... #differential # ... diagnosis #management #treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... with no early symptoms ... microglobulin Treatment ... • Richter’s Syndrome ... diagnosis #workup #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... diagnosis #hematology #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... → no immediate treatment ... : - Seen with AML ... (~20 %) and APL ... renal failure, pulmonary
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... leukoencephalopathy (PML ... Leishmaniasis Differential ... #Inflammatory #Syndrome ... #Differential #
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