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management differential hematology rheumatology algorithm secondary anemia hepatology nephrology neurology oncology pathophysiology systemic blood classification generalized hemophagocytic hepatopulmonary hlh lymphohistiocytosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... Diabetes Mellitus Liver ... • Cholestatic liver ... Myelodisplastic syndrome ... #generalized #dermatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Myelodysplastic Syndromes ... WBCs - Normal Liver ... Deficiency - Abnormal Liver ... Tests • Liver ... #Hematology
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
- Differential Diagnosis ... SBP <90, drop in ... Insufficiency, Liver ... , Severe Valve Disease ... Abdominal compartment syndrome
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... deficiency • Liver ... Gardner-Diamond syndrome ... #nonpalpable #dermatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... >10 mmHg - clinically ... and hepatorenal syndrome ... sarcoidosis) • Liver ... metastasis • Fatty liver
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
discoloration) • Liver ... • Nephrotic syndrome ... Systemic #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
syndromes Clinical ... thrombocytopenia • Liver ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Diagnosis #Management
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... chronic kidney disease ... : Alcohol use, Liver ... Myelodysplastic syndrome ... #causes #hematology
Asterixis is a type of negative myoclonus characterized by irregular lapses of posture of various body
characterized by irregular lapses ... associated with liver ... disease (hepatic ... hyperammonemia #PhysicalExam ... #clinical #diagnosis
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 Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
Streptococcal Toxic Shock Syndrome ... of invasive GAS disease ... GAS in 30% of cases ... (2+): kidneys, liver ... #STSS #treatment
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