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management neurology differential hematology causes algorithm signs classification erythematosus hemophagocytic hepatology hlh lupus lymphohistiocytosis oncology sle symptoms syndromes systemic acute
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
syndromes Clinical ... is the main clinical ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
- Differential Diagnosis ... SBP <90, drop in ... Insufficiency, Liver ... , Severe Valve Disease ... Abdominal compartment syndrome
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... : Fever, Arthralgia ... Differential Diaqnoses ... #diagnosis #management ... #treatment #rheumatology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... Anterior Cord Syndrome ... #diagnosis #pathophysiology ... signs #symptoms #msk ... #orthopedics #neurology
Korsakoff Syndrome Clinical Findings: • Confabulation: Usually initial phase of the disease • Anterograde amnesia: Memory impairment
Korsakoff Syndrome ... Clinical Findings ... initial phase of the disease ... Encephalopathy Treatment ... #neurology #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... #rheumatology # ... cerebritis #diagnosis
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
and less common diseases ... important, as early diagnosis ... and treatment can ... MRI lesions and clinical ... consistent with MS
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... age, however the disease ... • Bicytopenia Treatment ... #hematology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- Differential Diagnosis ... Osteoarthritis - Overuse syndrome ... Seronegative Reactive Syndrome ... #differential #diagnosis ... #msk #physicalexam
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... , ↓ Fibrinogen level ... • Autoimmune diseases ... #summary #rheumatology
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