13 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Encephalopathy, Cognitive Dysfunction ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... cerebritis #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... Treat primary cause ... Coagulation #diagnosis #causes ... #treatment #management
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm
Lifestyle  Modifications (Diet and Exercise) -> Start
Type 2 Diabetes ... Diagnosis and Management ... Algorithm Lifestyle ... • Secondary Causes ... #DMII #Classification
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
DEFINITION AND PATHOPHYSIOLOGY ... • Pathophysiology ... COMMON CAUSES + ... INITIAL MANAGEMENT ... ADVANCED MANAGEMENT
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... Alterations: - Sensory features ... • Infectious causes ... Myelitis #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... : 1) T-cell dysfunction ... failure Clinical Features ... Sarcoidosis #Diagnosis #Management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... TYPE IV RTA, TYPE ... ducts Clinical Features ... • 8%-27% for CNS ... Rheumatology #Diagnosis #Management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Kikuchi disease • Type-I ... syndrome Clinical Features ... and CNS • Headache ... mild cognitive dysfunction
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... PATHOPHYSIOLOGY ... • Pancreas: Type ... Thyroid (Riedel's), CNS ... complement • Classification
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
onset of illness features ... Related to the type ... pleural effusions, CNS ... unintentional weight loss, nausea ... Differential #Diagnosis #Management