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Causes, classification and compensatory responses to shock. Shock can be caused by any pathological process that leads
compensatory responses to shock ... Shock can be caused ... vasodilatation, myocardial dysfunction ... The cause of shock ... is often clinically
SEPSIS AND SEPTIC SHOCK DEFINITION AND PATHOPHYSIOLOGY • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
Life-threatening organ dysfunction ... cellular/metabolic dysfunction ... Infection + Organ dysfunction ... CLINICAL RECOGNITION ... CLINICAL FEATURES
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... of hypotension Shock ... death -> end-organ dysfunction ... death Common Clinical ... Distributive Shock
Shock Overview A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... of hypotension Shock ... death -> end-organ dysfunction ... death Common Clinical ... Distributive Shock
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... 64%) • Renal dysfunction ... 25%) • Hepatic dysfunction ... • Respiratory dysfunction ... (16%) • Shock
Sepsis - Diagnosis and Management Life-threatening organ dysfunction caused by a dysregulated host response to infection SEPTIC SHOCK
Life-threatening organ dysfunction ... infection SEPTIC SHOCK ... Patients w/ septic shock ... Clinical construct
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
Idiopathic LV dysfunction ... thrombus, RV systolic dysfunction ... Clinical • Under-recognized ... Pts: cardiogenic shock ... support for patients clinically
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
PRES) Overview Clinico-Radiological ... brain PRES Clinical ... PRES-Associated Clinical ... Infection/Sepsis/Shock ... unclear, endothelial dysfunction
Bedside Classification of Shock Hypovolemic shock - Vomiting, diarrhea, overdiuresis - Hemorrhage (GI, peritoneal, RP) Distributive shock
Classification of Shock ... Hypovolemic shock ... - Septic shock ... Acute valve dysfunction ... Prosthetic valve dysfunction
Cardiogenic Shock - Diagnosis and Management Summary Identifying Hypoperfusion from Cardiac Dysfunction • Exam: Congestion vs Hypoperfusion
Cardiogenic Shock ... Hypoperfusion from Cardiac Dysfunction ... #Cardiogenic #Shock
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