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Systemic Inflammatory Response Syndrome (SIRS) Criteria - Definitions of Sepsis, Severe Sepsis and Septic Shock Systemic Inflammatory
Inflammatory Response Syndrome ... Sepsis and Septic Shock ... Inflammatory Response Syndrome ... drop > 40 (Organ dysfunction ... hypoperfusion) Septic Shock
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
Inflammatory Response Syndrome ... Sepsis • Organ dysfunction ... hypoperfusion/organ dysfunction ... Septic Shock • ... #sepsis #sirs #shock
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Cardiogenic & Septic Shock ... Ischemia, Compartment Syndrome ... Microcirculatory dysfunction ... Mitochondrial dysfunction ... in Short Bowel Syndrome
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Encephalopathy Syndrome ... Clinico-Radiological Syndrome ... the neurologic syndrome ... Infection/Sepsis/Shock ... unclear, endothelial dysfunction
Bedside Classification of Shock Hypovolemic shock - Vomiting, diarrhea, overdiuresis - Hemorrhage (GI, peritoneal, RP) Distributive shock
Classification of Shock ... Hypovolemic shock ... - Septic shock ... Acute valve dysfunction ... Prosthetic valve dysfunction
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
region Viral Syndromes ... levels; dengue shock ... syndrome may lead ... capillary leak syndrome ... thrombocytopenia, and renal dysfunction
Cardiogenic Shock - Diagnosis and Management Summary Identifying Hypoperfusion from Cardiac Dysfunction • Exam: Congestion vs Hypoperfusion
Cardiogenic Shock ... Hypoperfusion from Cardiac Dysfunction ... #Cardiogenic #Shock
Mechanisms of acute right ventricular dysfunction/failure (RVD/RVF) #rightventricle #rvfailure #rvdysfunction
right ventricular dysfunction ... rightventricle #rvfailure #rvdysfunction
The Death Spiral: Increased RV Afterload (Acute PE) #Pathophysiology #PE #PulmonaryEmbolism #Embolism #DeathSpiral #Shock #RVDysfunction #RebelEM
#DeathSpiral #Shock ... #RVDysfunction
Non-lschemic Causes of Cardiogenic Shock: Beta-Blockers, Calcium Channel Blockers, Digoxin Myocarditis Cardiomyopathies (sarcoidosis, amyloidosis, Takatsubo, hemochromatosis) Valvular
of Cardiogenic Shock ... Fibrillation AV nodal dysfunction ... , Sinus nodal dysfunction ... #Cardiogenic #Shock
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