15 results
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Thiamine (B1) Deficiency ... Clinical Diagnosis ... nystagmus) - Cerebellar ... dysfunction and gait ... #diagnosis #criteria
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
- Diagnosis and ... Management Diagnosis ... nystagmus) • Cerebellar ... dysfunction (e.g. gait ... #Diagnosis #Management
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • Vitamin C deficiency ... Pernicious anemia/B12 deficiency ... collection with EDTA Pathophysiology ... ) - Waddling gait
Thyroid Function Pathway 

Hypothyroidism is a very common condition! Here's a repost of the pathway that
pathway that is deficient ... HIGH TSH and a low ... because if T4 is low ... Once diagnosed, ... Thyroid #Pathway #Pathophysiology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency ... - Differential Diagnosis ... rice, Cereals • Low ... #Differential #Diagnosis ... beriberi #nutrition #pathophysiology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... parasthesias, gait ... consider other diagnosis ... B12 #Cobalamin #Deficiency ... #diagnosis #management
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
Abnormal blood flow ... Protein C & S deficiency ... , ATIII deficiency ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Hypo-Mg2+ • Vitamin deficiency ... • Vitamin D deficiency ... , K, Mg2+) • Slow ... #Differential #Diagnosis ... #Pathophysiology
Wernicke's Encephalopathy 
CLINICAL TRIAD: only seen in 1/4 pts 
W.E. is often under diagnosed 
1. ENCEPHALOPATHY
is often under diagnosed ... . 5% have decr LOC ... GAIT ATAXIA (23% ... Primarily: Stance & gait ... Unlike Alcoholic Cerebellar
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Thrombocytopenia (HIT) - Diagnosis ... ♀, ↑Age, ESRD Pathophysiology ... thrombocytopenia Diagnosis ... Se/Sp but very slow ... - do not wait to