12 results
Wernicke Encephalopathy - Acute Thiamine (B1) Deficiency 
Clinical Diagnosis - Caine Criteria (2 out of 4):
Wernicke Encephalopathy ... Clinical Diagnosis ... nystagmus) - Cerebellar ... dysfunction and gait ... #diagnosis #criteria
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Wernicke Encephalopathy ... - Diagnosis and ... Management Diagnosis ... nystagmus) • Cerebellar ... dysfunction (e.g. gait
Wernicke's Encephalopathy vs Korsakoff Syndrome - Thiamine Deficiency

Wernicke's encephalopathy is a neurological condition due to longstanding
Syndrome - Thiamine Deficiency ... thiamine (vitamin B1) deficiency ... ataxia (broad-based gait ... #B1 #thiamine #deficiency ... Korsakoff #Syndrome #diagnosis
Wernicke Encephalopathy - Triad

Encephalopathy 
 • Disorientation 
 • Indifference 
 • Inattentiveness 
Ocular motor dysfunction
Wernicke Encephalopathy ... - Triad Encephalopathy ... Ataxia • Gait ... Syndrome #Triad #Diagnosis ... Neurology #Thiamine #Deficiency
Wernicke's Encephalopathy 
CLINICAL TRIAD: only seen in 1/4 pts 
W.E. is often under diagnosed 
1. ENCEPHALOPATHY
is often under diagnosed ... GAIT ATAXIA (23% ... Primarily: Stance & gait ... Unlike Alcoholic Cerebellar ... #diagnosis #triad
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Hypo-Mg2+ • Vitamin deficiency ... syndrome • Wernicke encephalopathy ... • Vitamin D deficiency ... #Differential #Diagnosis ... #Pathophysiology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency ... - Differential Diagnosis ... • Wernicke's Encephalopathy ... #Differential #Diagnosis ... beriberi #nutrition #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • Vitamin C deficiency ... Pernicious anemia/B12 deficiency ... collection with EDTA Pathophysiology ... ) - Waddling gait
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... lobes, brainstem, cerebellum ... , limb ataxia, gait ... rapidly progressive encephalopathy ... • VZV • HIV encephalopathy
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... Classic HIV Encephalopathy ... Diagnosis: MRI ... dysfunction like gait