23 results
High yield pharmacology notes
#pharmacology #antibiotics #nephrology #sideeffects #syndrome #medications
High yield pharmacology ... notes #pharmacology ... #antibiotics #nephrology ... sideeffects #syndrome #medications
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Osmotic diuretics (e.g ... Loop diuretic (e.g ... Thiazides-type diuretics (e.g ... nephron #diuretics #pharmacology ... #nephrology #medications
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... ) Loop agents (eg ... Adenosine #Nephron #Pathophysiology ... Sites #Action #nephrology ... #pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... phlebotomy High ... Medications 2. ... causes #potassium #high ... #nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... hypomagnesemia Hypokalemia ... - Insulin (high ... hypomagnesemia #Medications ... differential #diagnosis #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... phlebotomy High ... Medications 2. ... causes #potassium #high ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Etiology: • Medications ... heparinized tube) • ECG ... STOP offending medications ... Treatment #potassium #nephrology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Pathogenesis and Medications ... -5 inhibitors (e.g ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology ... #Urology
KDIGO Treatment algorithm for management of acute hyperkalemia in the emergency department
 • Place on cardiac
management of acute hyperkalemia ... monitor 12-lead ECG ... Consider dialysis #hyperkalemia ... treatment #potassium #high ... #nephrology #KDIGO