15 results
Treatment of hyperkalemia via kaliuresis 
step 1 = volume resuscitation if hypovolemic
step 2 = consider fludrocortisone
step
Treatment of hyperkalemia ... determine response to diuretic ... kaliuresis #management #criticalcare ... #treatment #diuretics ... #diuresis #nephrology
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
(e.g. mannitol) ... (e.g. furosemide ... (e.g. ... #pharmacology # ... nephrology #medications
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Pathophysiology - Diuretic ... Sites of Action Diuretics ... ) Loop agents (eg ... Sites #Action #nephrology ... #pharmacology
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
commonly used diuretics ... Spironolactone MCW Nephrology ... MCW_Nephrology #diuretics ... #pharmacology # ... Pharmacokinetics #halflife #comparison
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... Symport (Loop Diuretics ... ; High-Ceiling Diuretics ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
heparinized tube) • ECG ... Stabilization Treatments ... Redistribution Treatments ... Elimination Treatments ... #potassium #nephrology
Algorithm for the Treatment of Uremic Pruritus
Nonpharmacologic Treatments:
 • Daily topical emollient
 • Avoidance of extremes
Algorithm for the Treatment ... Evidence-Based Off-Label Pharmacologic ... Treatments of Uremic ... nalfurafine 2.5 mcg ... #management #nephrology
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
with caution - e.g ... #pharmacology #comparison ... #treatment #medications
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
is not desired (e.g ... is not desired (e.g ... Vasopressors #Inotropes #comparison ... #table #pharmacology ... #criticalcare
Checklist for Treatment of Delirium in the ICU 

Remove causative factors 
 - 
Exclude hypoglycemia if
Checklist for Treatment ... consider empiric treatment ... interruption (e.g ... sleeping, administer pharmacologic ... #MICU #CriticalCare