13 results
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... Hematopoietic stem ... HLA-selected products (e.g ... #Indications #Hematology ... #BloodBank #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... (CNS) dysfunction ... underlying disease (eg ... • Infection (eg ... Diagnosis #Management #Hematology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... (e.g. oculomotor ... AQP4-lgG disease; e.g ... pain • Extra-CNS ... autoimmune disorders (Systemic
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
halt nail growth (e.g ... • Nephrotic syndrome ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm ... #causes
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... central nervous system ... (CNS) involvement ... skull neoplasms (e.g ... MRI lesions and clinical
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... Cryoglobulins Cause ... : • Clinical triad ... tissue disorder (e.g
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... • Malignancy (e.g ... Endocrine disorders (e.g ... Clinical Features ... and CNS • Headache
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... vision changes, etc ... identifies 85 to 95% of cases
This infographic provides a mnemonic tool called “WOBBLER” for assessing an ECG (electrocardiogram) in cases of
evaluate potential causes ... pathway that can cause ... heart’s conduction system ... QT syndrome, both ... Clinical Utility