31 results
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
• Thrombus (e.g ... Myeloproliferative disorders ... (eg. polycythemia ... Inflammatory • Systemic ... #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Sequestration Disordered ... Rare • Drugs (e.g ... Disease Vascular System ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... or if a primary hematologic ... #Workup #hematology
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive 
ulceration of the skin.
Gangrenosum: Autoimmune disorder ... vasculitis which causes ... ulceration of the skin ... a number of systemic ... #Photo #Dermatology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... to Systemic Diseases ... halt nail growth (e.g ... #Secondary #dermatology ... Diagnosis #Algorithm #causes
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... for secondary causes ... signs or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Syndrome: • Clinical ... Henoch-Schönlein purpura) • Cutaneous ... (e.g. systemic
Primary Dermatological Lesions
Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... altered colour e.g ... . e.g. psoriasis ... a generalized disorder ... #Diagnosis #Dermatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
toxic aetiology: Skin ... of information (e.g ... for alternative causes ... Hepatic vascular disorder ... (e.g. ascites),