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diagnosis differential management algorithm anemia treatment workup rheumatology disorders elevatedmcv erythematosus hepatopulmonary lupus macrocytosis sle syndrome systemic abscess acidosis aplastic
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Iron Deficiency (Eg ... Blood Loss, Occult ... Other • e.g ... HgbE, HgbC, etc. ... #Hematology
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Consensus Indications ... for Irradiated RBC ... HLA-selected products (e.g ... #Irradiation #RBC ... #Indications #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
family history - Medications ... plateletcount), peripheral blood ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... #Workup #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Chemotherapy (e.g ... disease, McLeod blood ... Liver disease, Etc ... differential #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... • Intrinsic RBC ... deficiencies (e.g ... differential #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Algorithm Normal Blood ... Neutrophils - Low RBC ... Increased Requirement (e.g ... #Hematology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
inflammation (eg ... been reported (eg ... AIH-PBC Overlap ... of Hepatitis (eg ... Diagnosis #Management #Hepatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm INDICATIONS ... • Peripheral blood ... for secondary causes ... signs or symptoms (eg ... Differential #diagnosis #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
of information (e.g ... duration), Several medications ... for alternative causes ... vascular disorder (e.g ... Diagnosis #Algorithm #hepatology
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
Indications for ... chemotherapy, etc ... possible malignancy (e.g ... on peripheral blood ... Electrophoresis #SPEP #Hematology
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