14 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
purpura to mucosal bleeding ... underlying disease (eg ... • Infection (eg ... Diagnosis #Management #Hematology ... #Rheumatology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... Immunodeficiency Disorder, etc ... antithymocyte globulin, etc ... HLA-selected products (e.g ... #Indications #Hematology
Clubbing of the Fiingers: Bulbous appearance of the distal fingers associated with a 
number of uncommon
lung conditions (e.g ... , IPF, cancer, etc ... Images #Clinical ... #Photo #Clubbing ... #Fingernails #UCSDH
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Immunosuppression (e.g ... Autoimmune diseases (e.g ... Hepatosplenomegaly, cytopenias(bleeding ... Malignancies (eg ... #differential #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... inflammation, leading ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
chemotherapy, etc ... possible malignancy (e.g ... pain, abnormal bleeding ... Electrophoresis #SPEP #Hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... antiinflammatory properties e.g ... Tetracyclines etc ... #Rheumatology # ... diagnosis #management #Dermatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... Hyperviscosity Syndrome ... : • Clinical triad ... tissue disorder (e.g ... classification #rheumatology
Clubbing of the Fiingers: Bulbous appearance of the distal fingers associated with a number of uncommon
lung conditions (e.g ... IPF, cancer, etc ... Images #Clinical ... #Photo #Clubbing ... #Fingernails #SchamrothsSign
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... Drug history, e.g ... connective tissue, e.g ... Marfan syndrome, ... pediatrics #diagnosis #hematology