27 results
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
• Provoked (e.g ... - No other workup ... Hypercoagulable #Workup ... #hematology #diagnosis ... #algorithm #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Iron Deficiency (Eg ... Other • e.g ... HgbE, HgbC, etc. ... Algorithm #Causes #Hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
hemolytic anemia (e.g ... Smear #Analysis #hematology ... interpretation #clinical
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... signs or symptoms (eg ... Differential #diagnosis #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Immunodeficiency Disorder, etc ... antithymocyte globulin, etc ... HLA-selected products (e.g ... #Indications #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Post-splenectomy, Etc ... Liver disease, Etc ... valve induced, Etc ... differential #diagnosis #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
of substrate (e.g ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... count, D-dimer, egg ... hemolytic #anemia #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... function test, ANA (e.g ... Diagnosis #Causes #Workup ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Immunosuppression (e.g ... Autoimmune diseases • Clinical ... Autoimmune diseases (e.g ... Malignancies (eg ... #differential #hematology