19 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
• Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... cerebritis #diagnosis #management
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
cardiac syncope, e.g ... carotid sinus syndrome ... further guide management ... orthostatic vital sign ... and an initial ECG
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... (e.g. oculomotor ... AQP4-lgG disease; e.g ... disorders (Systemic lupus ... neurology #symptoms #signs
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Myasthenia Gravis Pharmacologic ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... (e.g. haloperidol ... hyperthermia crisis (late sign
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
underlying disease (eg ... SJIA], systemic lupus ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
Torsades de Pointes - Management ... Algorithm Drugs ... Syndrome Electrolyte ... 1b (lidocaine)- case ... #Algorithm
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... renal failure Clinical ... of diagnosis (e.g ... skin (16-32%): lupus ... #Signs #Symptoms