27 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... antithymocyte globulin, etc ... HLA-selected products (e.g ... #Indications #Hematology ... #BloodBank #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... underlying disease (eg ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
(e.g., long QT ... syndrome, ARVC) ... Substances • Digoxin toxicity ... Symptoms: • ... 300 = NSVT EKG
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... - Summary Clinical ... IU/I • SAMS clinical ... (SAMS-CI) • EMG ... myopathy #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... antiinflammatory properties e.g ... Tetracyclines etc ... #Rheumatology # ... diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... renal failure Clinical ... of diagnosis (e.g ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Histamine Fish Toxicity - Inadequate refrigeration increases enzyme from bacteria on fish 
Clinical 
• Skin flushing,
bacteria on fish Clinical ... Oral burning, nausea ... palpitations • Symptoms ... eating fish Management ... Antihistamines (e.g
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
(e.g., acute respiratory ... distress syndrome ... (e.g., chronic ... Exclude other causes ... Pulmonary #diagnosis #management