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Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... repolarization causes ... prolonged PR and QT ... #EKG #ECG #Changes ... #Progression #Table
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Infiltrative disorders (e.g ... in kidneys) - Medications ... (e.g. lithium, ... renal diseases (e.g ... #Causes
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
and sodium • Dosing ... binds magnesium • Dosing ... and calcium • Dosing ... #medications #pharmacology ... #table #comparison
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... mmol/L - Consider cause ... guided by clinical ... scenario, ECG and ... Prevention - Consider cause
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
with caution - e.g ... #pharmacology #comparison ... #treatment #medications ... #dosing #drugs ... #table #pharmacotherapy
Medications for the Treatment of Hyperkalemia
The goals of acute treatment are to prevent potentially life-threatening cardiac
Medications for ... , changes on ECG ... , and Table 3 summarizes ... medications used ... #Management #Medications
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... Resistance, Main Uses ... Book of Critical ... Vasopressors #Properties #Table ... Effect #Management #Comparison
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... heparinized tube) • ECG ... only if no clear cause ... Elimination (see Table ... STOP offending medications
Inpatient Management of Opioid Use Disorder: Methadone vs Buprenorphine - Comparison Table

Some patients may decline buprenorphine
Buprenorphine - Comparison ... Table Some patients ... interested in medication ... assisted treatment ... Dosing usually begins
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
of information (e.g ... duration), Several medications ... non-essential drug/HDS treatments ... for alternative causes ... vascular disorder (e.g