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differential management algorithm transaminitis workup anemia comparison reactions atlas coagulation dili elevatedmcv failure function hepatitis interpretation laboratory macrocytosis microscopy nomenclature
Table of Causes of Acute Liver Injury #Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes ... of Acute Liver Injury ... #Diagnosis #Hepatology ... #Acute #Liver # ... Injury #Causes #
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... Liver Injury ... Transaminitis #diagnosis ... #differential #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... - Drug-Induced liver ... injury - Viral ... #Hepatology #Diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... Hepatopathy • Acute ... injury) • Ischemic ... #hepatology #transaminitis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... #differential #Diagnosis ... #algorithm #gastroenterology ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... for alternative causes ... dechallenge • Acute ... #Injury #Diagnosis ... #Algorithm #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #diagnosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Diagnosis Hepatocellular ... #Diagnosis #Causes ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... intestines, White blood ... #chemistry #diagnosis ... #differential #Hepatology ... transaminitis #LFTs
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