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management differential hemophagocytic hlh lymphohistiocytosis syndrome algorithm arteritis atlas blood bloodcell chemistry dili druginduced gca giantcell hemeonc hepatorenal hrs injury
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... disease, Etc. ... valve induced, Etc ... #differential #diagnosis ... #hematology #microscopy
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... to HDS, drugs, OTC ... non-essential drug/HDS treatments ... #Injury #Diagnosis ... #Algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... intestines, White blood cells ... #chemistry #diagnosis ... #differential #Hepatology ... #transaminitis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... Low or absent NK cell ... lymph node, or liver ... • Bicytopenia Treatment ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Management #Hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... (GCA) Giant cell ... vision changes, etc ... thrombocytosis, transaminitis ... Treatment of GCA
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
by uncontrolled activation ... search for and treatment ... - Elevated liver ... Treatment Approach ... #Management #Hematology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
sympathetic + ADH activation ... Diagnosis (Clinical ... Treatment Overview ... insult (e.g., alcohol ... Hepatorenal #Syndrome #Hepatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... eruptions, diarrhea, liver ... potassium from lysed cells ... #Transfusions #diagnosis ... #management #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
red bone marrow, e.g ... common - GI tract, liver ... Diagnosis? ... Bone marrow Treatment ... #Workup #Hematology
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