22 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Medications - Heparin ... ) • Advanced Liver ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
- Differential Diagnosis ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Appearance of Liver Lesions on Computed Tomography (CT) - Arterial Phase, Portal Venous Phase and Delayed
Appearance of Liver ... #Lesions #Hepatic ... #differential #diagnosis ... #comparison #table ... #appearance #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... disease, Hepatic ... presentation: Hepatic ... #Injury #Diagnosis ... #Algorithm #hepatology
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... #Lesions #Hepatic ... #differential #diagnosis ... #comparison #table ... #appearance #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... hemorrhagic skin lesions ... deficiency • Liver ... #Differential #Diagnosis ... #hematology #rheumatology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
(e.g. methotrexate ... disease, Etc. ... valve induced, Etc ... #differential #diagnosis ... #hematology #microscopy
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
or not by the liver ... the blood The diseased ... , Pancreatitis etc ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... Prolonged #Causes #diagnosis ... #differential #hematology ... #coagulation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... Disease: - Impaired ... 100mg/dL) - Heparin ... #diagnosis #causes ... treatment #management #hematology