11 results
Shotgun Laboratory Testing for Severe Acute Livery Injury

https://www.journalofhospitalmedicine.com/jhospmed/article/143598/hospital-medicine/ammonia-levels-and-hepatic-encephalopathy-patients-known

#TWDFNR #Testing #Laboratory #LiverInjury #Diagnosis #Workup #Hepatology #EBM #ChoosingWisely
Shotgun Laboratory ... for Severe Acute Livery ... ammonia-levels-and-hepatic-encephalopathy-patients-known ... #LiverInjury #Diagnosis ... #Workup #Hepatology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... unfractionated heparin ... Reduced liver synthesis ... #Causes #diagnosis ... #differential #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... disease, Hepatic ... presentation: Hepatic ... #Injury #Diagnosis ... #Algorithm #hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Medications - Heparin ... ) • Advanced Liver ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... Findings in Hepatic ... glycogen stores - Prolonged ... #Hepatology #Laboratory ... #Diagnosis #Testing
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... . heparin contamination ... • Reduced liver ... #Causes #diagnosis ... #differential #hematology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... ) or metabolic liver ... Possible drug-induced liver ... Presence of atypical laboratory ... #Hepatology #AIH
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... , AIH diagnosis ... Necrosis) If mild laboratory ... #Hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... ) or metabolic liver ... Presence of atypical laboratory ... #diagnosis #Alcoholic ... #hepatology #criteria
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... venipuncture sites Laboratory ... DIC • Severe Liver ... #Coagulation #diagnosis ... treatment #management #hematology