17 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... (MD) - Diagnosis ... old, ~10,000 new cases ... #MDS #Diagnosis ... #hematology #oncology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
- Differential Diagnosis ... HgbE, HgbC, etc. ... #Macrocytosis #elevatedMCV ... #Differential #Diagnosis ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... - Differential Diagnosis ... Myelodysplastic Syndromes ... #Macrocytosis #elevatedMCV ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... NSAIDs, quinine, etc ... infection (TB), MDS ... antiphospholipid syndrome ... #Framework #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... HLA-selected products (e.g ... Daniela Hermelin, MD ... #Indications #Hematology ... #BloodBank #Management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... (MDS) (normal or ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... underlying disease (eg ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... antiinflammatory properties e.g ... Tetracyclines etc ... diagnosis #management ... #Dermatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... normal in mild cases ... hemophilia type (e.g ... Avoid meds that ... #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology