12 results
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... of high parity blood ... #Transfusion #Reactions ... #hematology #diagnosis ... #comparison #table
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... Other: Transfusion reaction ... #differential #diagnosis ... #hematology #anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... plateletcount), peripheral blood ... function test, ANA (e.g ... #Differential #Diagnosis ... Causes #Workup #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... purpura & severe thrombocytopenia ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... haptoglobin, ↑LDH, etc ... purpura & severe thrombocytopenia ... #Transfusion #diagnosis ... #management #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... allergy, drug reaction ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
- Differential Diagnosis ... Causes: Chronic Blood ... HgbE, HgbC, etc. ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Chemotherapy (e.g ... disease, McLeod blood ... #differential #diagnosis ... #hematology #microscopy
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
leukopenia, anemia, and thrombocytopenia ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
chemotherapy, etc ... possible malignancy (e.g ... on peripheral blood ... Electrophoresis #SPEP #Hematology ... #Diagnosis