14 results
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
• Thrombus (e.g ... Myeloproliferative disorders ... (eg. polycythemia ... Felty's Disease • Serum ... Algorithm #Causes #Hematology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Hydroxychloroquine Serum ... Special cases (e.g ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Volume (MCV) - Differential ... Iron Deficiency (Eg ... Other • e.g ... HgbE, HgbC, etc. ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... (usually IgM) (e.g ... lymphoproliferative disorders ... #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... function test, ANA (e.g ... #Differential # ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... signs or symptoms (eg ... #Algorithm #Differential ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Increased Requirement (e.g ... Anemia - Low Serum ... • Small Bowel Disorder ... Algorithm #Causes #Hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
are Igs in the serum ... level • Low serum ... (e.g. systemic ... lupus erythematosus ... classification #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Malignancy (e.g ... (e.g. thyroid disease ... , and elevated serum ... Erythematosus #Diagnosis #Rheumatology
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
Indications for Serum ... amyloidosis, or related disorder ... chemotherapy, etc ... possible malignancy (e.g ... Electrophoresis #SPEP #Hematology