15 results
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
: • Acute or chronic ... alterations (e.g ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Wilson's disease Pulmonary ... disease, Vasculitis (e.g ... #pain #differential ... #diagnosis #rheumatology
Inflammatory Joint Pain - Differential Diagnosis Algorithm 
Monoarticular
 • Gout (Podagra, Tophi)
 • Pseudogout
 • Early
Pain - Differential ... • Reactive (e.g ... Enteropathic (e.g ... Rheumatic Fever Acute ... Enteropathic (e.g
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis ... Differential Diagnosis ... Gonococcal/Lyme etc ... - Autoimmune Rheumatologic ... Joint #pain #Differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Prednisone 5mg/kg ... effusions, weight gain ... Imaging: CXR- pulmonary ... initiation • Differential
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... nonerosive inflammatory arthritis ... antiinflammatory properties e.g ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for Acute ... inflammatory disease (e.g ... Chemistry profile (e.g ... , and low back pain
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
not be subtle e.g ... very remarkable w/differential ... E.g. 80 yo ESR cutoff ... claudication: pain ... them, but urgent rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... permanent alopecia Differential ... • Malignancy (e.g ... Endocrine disorders (e.g ... : • Joint pain