26 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... #neurology #rheumatology ... cerebritis #diagnosis #management
Priapism 

Secondary Causes:
Medications- intracavernosal injections, anticoagulants, PDE5 inhibitors, alpha blockers, methylphenidate, cocaine
Any hyperviscosity syndrome (SCD, leukemia,
Secondary Causes ... : Medications- ... hyperviscosity syndrome ... leukemia, myeloma, etc ... Priapism #Diagnosis #Management
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Consensus Indications ... disorders (DiGeorge Syndrome ... HLA-selected products (e.g ... #Hematology #BloodBank ... #Management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
family history - Medications ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... or if a primary hematologic ... #Workup #hematology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... • Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... levels #lupus #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... underlying disease (eg ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... post-operative phenomenon, medications ... , etc. ... bolus of 0.9% NS ... #hyponatremia #nephrology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... #diagnosis #management ... signs #symptoms #rheumatology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
with previously stable ... heart failure, neurologic ... White-coat syndrome ... Neurologic disorders ... Differential #Diagnosis #indications
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... antiinflammatory properties e.g ... Tetracyclines etc ... #Rheumatology # ... diagnosis #management