34 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... methotrexate) • Drugs ... Non-lmmune: • HELLP Syndrome ... Algorithm #Causes #Hematology
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
toxidrome is a syndrome ... caused by specific medications ... barbituates, “Z-drugs ... antihistamines #Diagnosis ... #Table #Anticholinergics
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Liver disease, Etc ... disorders, Oxidative drugs ... #differential #diagnosis ... #hematology #microscopy
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... infection) - Drugs ... #hematology #anemia
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
and Vasoactive Drugs ... rupture, VSD, etc ... #inopressors #diagnosis ... #management #comparison ... #table
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Blood Smear • Drugs ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... DILI) - Stepwise Diagnosis ... duration), Several medications ... Liver #Injury #Diagnosis ... #Algorithm #hepatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... - Antithyroid medications ... #oncology #hematology ... #diagnosis #management
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g ... Anticoagulant Medications ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
- Differential Diagnosis ... Neoplastic / Hematologic ... • Anemia • ... Abuse (e.g. ... Chronic Fatigue Syndrome