35 results
Torsades de Pointes 
•Precipitated by drugs that prolong the QT interval 
•Class IA antidysrhythmics (procainamide, quinidine)
that prolong the QT ... hypomagnesemia, hypokalemia ... TorsadesDePointes #Diagnosis ... #Cardiology #ECG ... #EKG
Torsades de Pointes
• "Twisting of the pointes" 
• QRS axis swings from positive to negative direction
that prolong the QT ... Hypomagnesemia Hypokalemia ... TorsadesDePointes #Diagnosis ... #Cardiology #ECG ... #EKG
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Infiltrative disorders (e.g ... - Medications (e.g ... - Chronic hypokalemia ... renal diseases (e.g ... #Diagnosis #Table
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... prolonged PR and QT ... #Diagnosis #Hyperkalemia ... #EKG #ECG #Changes ... #Progression #Table
Constipation - Differential Diagnosis Algorithm
Diet/Lifestyle
 • Fibre
 • Calories
 • Fluid
 • Exercise
 • Psychosocial
Medications
 •
Diagnosis Algorithm ... Active Medications (e.g ... Cation Related (e.g ... Anticholinergic (e.g ... Hypothyroidism • Hypokalemia
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hyporeflexia: • Hypercalcemia ... polyneuropathy (e.g ... Hyperreflexia: • Hypocalcemia ... Testing #Causes #differential ... #diagnosis #table
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
metastases, Infection (e.g ... Metabolic causes (e.g ... ., hypokalemia, ... disease, Drugs (e.g ... #Diagnosis #Differential
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... heparinized tube) • ECG ... emcrit.org/ibcc/hyperkalemia ... management of hyperkalemia ... #Hyperkalemia
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
- Malignancy (e.g ... CNS pathology (e.g ... hemorrhage) - Pulmonary ... pathology (e.g. ... #Diagnosis #Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... • LDH ↑ • Hyperkalemia ... Dialysis for severe hyperkalemia ... causes #treatment #nephrology