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diagnosis management blood reactions product syndrome arteritis bloodbank coagulation deficiencies deficiency differential druginduced essential et gca giantcell hemolyticuremicsyndrome hus indications
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Irradiated RBC Transfusions ... Intrauterine and neonatal transfusions ... antithymocyte globulin, etc ... HLA-selected products (e.g ... #Indications #Hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
: 33% • Treatment ... : No • Treatment ... #Reactions #hematology ... #diagnosis #comparison ... #table
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... in recipient (e.g ... haptoglobin, ↑LDH, etc ... Associated Graft Versus ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... Non-Hemolytic Transfusion ... haptoglobin, ↑LDH, etc ... Associated Graft Versus ... diagnosis #management #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Diuretics, PRBC transfusion ... organ damage • Treatment ... Low calcium • Treatment ... unless worrisome EKG ... diagnosis #management #hematology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
the mainstay of treatment ... Chronic Graft-Versus-Host ... seen after blood transfusion ... Differential #Diagnosis #comparison ... #table #dermatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... evocative of SLE versus ... life-threatening • Treatment ... druginduced #lupus #sle #comparison ... #table #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
and lower jaw Treatment ... antiinflammatory properties e.g ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
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