14 results
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
DOAC, direct oral ... #DOAC #VTE #Malignancy ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
Patient risk stratification ... algorithm for the treatment ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
Bleeding risk calculators ... validated for VTE treatment ... of withholding anticoagulation ... Calculators #Anticoagulation ... #Factors #Hematology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
patients on chronic anticoagulation ... table ... and procedural bleeding ... with a very low bleeding ... anticoagulation
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... thereby leading ... #Chemotherapy #Oncology ... #Hematology #Interactions ... #Table #Pharmacology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... lead to severe bleeding ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
hemophilia type (e.g ... Classify severity Treatment ... by a hemophilia treatment ... risk ... #hematology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Avoid Warfarin and DOAC ... during Delivery • Stable ... Period • Breast-feeding ... suggest prophylactic anticoagulation ... management #cardiology #treatment
Longterm Venous Thromboembolism Treatment Algorithm
Treat for 3 months and reassess
 • Isolated distal DVT (without cancer)
Thromboembolism Treatment ... PE - High Bleeding ... - Not High Bleeding ... Algorithm #management #hematology ... #anticoagulation
Bleeding Risk for Various Invasive/Surgical Procedures
Low Risk:
 • Dental extractions (1 or 2 teeth), endodontic (root
Bleeding Risk for ... Cataract surgery • Dermatologic ... placement (if bridging anticoagulation ... polypectomy) #Bleeding ... Perioperative #Procedures #Table