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diagnosis management differential syndrome algorithm blood comparison dress product transfusion arteritis compared damage dili disorders druginduced eosinophil eosinophilia erythemas exposure
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
allergy, drug reaction ... glucocorticoid treatment ... signs or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment Stop offending agents: • List as allergies
Drug Reaction with ... DRESS) Syndrome Treatment ... cyclosporine, IVIG etc ... • Skin: topical ... #Management #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
characterized by extensive skin ... Edema in 70% of cases ... Skin involvement ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... without other cause ... : 33% • Treatment ... #hematology #diagnosis ... #comparison #table
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
toxic aetiology: Skin ... to HDS, drugs, OTC ... non-essential drug/HDS treatments ... for alternative causes ... Diagnosis #Algorithm #hepatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
haptoglobin, ↑LDH, etc ... Causes purpura & ... TRALI): Leading cause ... infections with skin ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... Causes purpura & ... infections with skin ... diagnosis #management #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... antiinflammatory properties e.g ... Tetracyclines etc ... diagnosis #management #Dermatology
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
centrifugum • A chronic skin ... foods, stress, etc ... gyratum repens • A skin ... Erythemas #comparison #table ... differential #diagnosis #dermatology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... Constitutional disorders, eg ... Idiosyncratic drug reactions ... Idiosyncratic drug reactions-most ... #hematology
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