35 results
Treatments for Sickle Cell disease

#Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
Treatments for Sickle ... Cell disease ... sicklecells #sickle #hematology ... #anemia #clinical
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
hemolytic anemia (e.g ... : Sickle cell disease ... Bite cells: G6PD ... Smear #Analysis #hematology ... interpretation #clinical
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
megaloblastic anemia Treatment ... Consider stem cell ... (transfusions, antibiotics ... diagnosis #management #treatment ... #hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
malnutrition, Antibiotics ... Malabsorption (e.g ... warfarin, DOACs (e.g ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... Drugs (Beta lactam antibiotics ... . sickle cell disease ... differential #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... Orange or Hep C Clinical ... or basket cells ... microglobulin Treatment ... workup #oncology #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... non-specific red cell ... polychromatophilic cells ... count, D-dimer, egg ... hemolytic #anemia #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
management #algorithm #pharmacology ... #treatment #medications ... #table #pharmacotherapy ... decisionaid #cardiology #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Immunosuppression (e.g ... Autoimmune diseases • Clinical ... Noncontiguous spread • Clinical ... Lymphomas • Other hematologic ... #differential #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Post-splenectomy, Etc ... Liver disease, Etc ... valve induced, Etc ... differential #diagnosis #hematology