23 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Fever, Arthralgia/arthritis ... fraction < 20% Differential ... #management #treatment ... #rheumatology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Origin (FUO) - Differential ... Malignancy: - Hematologic ... Lupus, Rheumatoid arthritis ... Sarcoidosis, Adult onset Still's ... #Origin #FUO #Differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
IBD, Whipple's disease ... infection • Still's ... , Vasculitis (e.g ... #joint #pain #differential ... #diagnosis #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... #Disease #AOSD ... #rheumatology #diagnosis ... #management #treatment
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Symptoms of Joint Disease ... categories of joint disease ... mainly or only during ... Joint #Pain #MSK #rheumatology ... approach #workup #differential
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... or extremities during ... Treatment - Mild ... : NSAIDS Treatment ... #management
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... thrombocythemia), Autoimmune disease ... Syndrome #Diagnosis #Management ... #treatment #hematology ... #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... taking a shower and moving ... Gonococcal/Lyme etc ... • Adult onset Still's ... Joint #pain #Differential
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
) Differential Diagnosis ... SLE, Reactive arthritis ... , AS Treatment: ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Adult-onset Still ... idiopathic arthritis ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology