51 results
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... suspicion of severe disease ... - Sickle cell disease ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... (SLE) Clinical ... Cerebrovascular Disease ... autoantibodies that will cause ... permeability Diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... Evolution: Chronic disease
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... • Ulcerated, erythematous ... Differential Diagnosis ... #rash #diagnosis
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
structural heart disease ... and an initial ECG ... should be guided by clinical ... the underlying disease ... The treatment strategy
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
screening for disease ... with established disease ... normal in mild cases ... Avoid meds that ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause ... Treatment: • ... of emergency, ICU
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Demyelinating Disease ... (MS), Epidural ... heavy metals), Critical ... #differential #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... fever syndromes Clinical ... Fever is the main clinical ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
cryoglobulinemia vasculitis - Diagnosis ... , causes and management ... cryoglobulinemia vasculitis Clinical ... neuropathy Treatment ... with refractory disease