51 results
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... calculating the eGFR ... to remember the eGFR ... #Nephro #CKD #EGFR
Renal Failure Prognosis - The eGFR and proteinuria offers a general prognosis as demonstrated in the
Prognosis - The eGFR ... #CKD #EGFR #Proteinuria
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Cetuximab and other EGFR ... in Na-KATPase, EGFR
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
maximum dose eGFR ... recommended dose eGFR
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
- 85% • Mean eGFR ... follow-up • eGFR
Table 1. Equations for estimated glomerular filtration rate (eGFR) in adults based on serum creatinine concentration*.
#Diagnosis
filtration rate (eGFR ... CockcroftGault #EGFR
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
45-60 Monitor eGFR
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
not initiate if eGFR ... not continue if eGFR
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
months - eGFR ... HRS-CKD - eGFR