15 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
s Syndrome: Pathogenesis ... biliary cirrhosis (PBC ... erythematosus (SLE) Signs ... #Pathophysiology ... #Diagnosis #Signs
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... myasthenia Diagnosis ... Serologic and EMG ... test - Cogan sign ... - Peek sign
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... DIC, HELLP - Grafts ... , Valves, AS ... Drug-associated, PCH ... , Evans Syndrome
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
, Anti-gp210 - Primary ... biliary cirrhosis (PBC ... Anti-TSHR - Graves ... Endomyseal antibody (EMA ... Associations #diseases #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... Pathophysiology ... Signs and Symptoms ... Diagnosis: • ... bile ducts Differential
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... / Symptoms / Complications ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... severe clinical complications ... deficiency • Primary ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Diagnosis Framework ... Postsynaptic: Myasthenia Gravis ... Lack of UMN/LMN signs ... #Diagnosis #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Diagnosis Approach ... previously stable values ... hypertension and signs ... renal bruit or signs ... Hypothyroidism, Primary
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... Diagnosis Framework ... dysfunction • PSC ... appendages • FMF ... Chronic #Causes #Differential