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management barre cord guillain spinal spinalcord algorithm als amyotrophic apml autoimmune caudaequina causes differentiation disorders equina gbs guillainbarre hematology lateral
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
Cauda Equina Syndrome ... lumbar spine • MCC ... Diagnosis: • ... cord infarct • HIV ... #neurology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... Campylobacter jejuni - HIV ... Guillain-Barre Diagnosis ... nerve roots and cauda ... #treatment #neurology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Diagnosis Framework ... Lower roots -> Cauda ... , HIV, CMV, HTLV ... MCTD, Sjogren syndrome ... #neurology #differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... initiation • Differential ... fluid overload, PCC
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... syphilis, and HIV ... involvement Cauda ... #lesions #differential ... #diagnosis #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
immunodeficiency virus (HIV ... than one after symptom ... the underlying pathophysiology ... nerve roots and cauda ... #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... fasciculations Common Symptoms ... EMG: LMN Signs in ... conditions listed in differential ... Lateral #Sclerosis #neurology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Diagnosis Framework ... Aldolase levels • EMG ... weakness + atrophy- Hip ... #rheumatology #differential
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